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PROTEINES DE LIAISON INTERLEUKINE 13
专利权人:
AbbVie Bahamas Ltd.
发明人:
申请号:
EP07873427.4
公开号:
EP2064336B1
申请日:
2007.09.07
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention encompasses IL-13 binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hIL-13 and neutralize hIL-13 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Method of making and method of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hIL-13 and for inhibiting hIL-13 activity, e.g., in a human subject suffering from a disorder in which hIL-13 activity is detrimental.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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