New aptamer that specifically binds to human tau protein or its fragment, useful e.g. in vitro for isolating, purifying and/or detecting tau protein, and to treat cerebral infarction, pick disease and/or progressive supranuclear palsy
Die vorliegende Erfindung bezieht sich auf Aptamere, die spezifisch an humanes Tau-Protein oder ein Fragment davon binden, deren Verwendung und auf einen Kit enthaltend ein solches Aptamer.Aptamer that specifically binds to human tau protein or its fragment, is new. Independent claims are included for: (1) kit comprising the aptamer； (2) a method for the purification of human tau protein or its fragments comprising contacting a sample containing human tau protein or its fragments with the aptamer and separating the obtained complex of aptamer and bound tau protein or its fragments from the remaining sample； and (3) a method for detection of human tau protein or its fragments comprising contacting a sample to be tested with the aptamer and detecting a binding event between the aptamer and the human tau protein or its fragment. - ACTIVITY : Cerebroprotective； Vasotropic； Neuroprotective； Nootropic； Antiparkinsonian. - MECHANISM OF ACTION : None given.
