Tina P. Dasbach;Kacee B. Ender;Robert E. Scheid, Jr.;Akshay Bellare;Tim D. Cabelka;Karl V. Jacob;Ka Chun A. Chan
发明人:
Tim D. Cabelka,Akshay Bellare,Ka Chun A. Chan,Tina P. Dasbach,Kacee B. Ender,Karl V. Jacob,Robert E. Scheid, Jr.
申请号：
US12595627
公开号：
US08877249B2
申请日:
2008.02.28
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A dosage form for controlled release is produced from a composition comprising a granular material having a mean particle diameter of 150 to 350 micrometers and a compactibility resulting in a compact with a tensile strength of at least 1.7 MPa when the granular material is subjected to a compaction pressure of 266 MPa, at least 80 percent of the granular material being a water-soluble cellulose ether, water-soluble cellulose ester, an alkylene oxide homo- or copolymer, or a blend thereof； and an active ingredient.
