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Beta-peptides with antifungal activity
专利权人:
Sean P. Palecek
发明人:
Sean P. Palecek,Samuel H. Gellman,William C. Pomerantz,Amy J. Karlsson
申请号:
US11849751
公开号:
US09168329B2
申请日:
2007.09.04
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention is directed to the design, synthesis and use of various β-peptides exhibiting antifungal activity. The β-peptides are relatively short in length, adopt globally amphiphilic conformations, and cause little lysis of human red blood cells at concentrations that kill Candida albicans, a common human fungal pathogen.
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