R. John Collier,Isaac Chiu,Bradley L. Pentelute,Keith Alan Foster,Shilpa Palan,Sai Man Liu
申请号：
US15755544
公开号：
US20180244731A1
申请日:
2016.08.26
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Embodied herein are engineered fusion proteins that bind and target nociceptor neurons, compositions comprising these engineered fusion proteins, and methods for treatment of pain using these engineered fusion proteins or compositions containing the engineered fusion proteins. The engineered fusion proteins contain domains derived from protein toxins such as the anthrax toxin, clostridial botulinum family of toxins, disulphide-containing toxins, and AB component type toxins.
