您的位置: 首页 > 农业专利 > 详情页

MYBL2 PEPTIDES AND VACCINES CONTAINING THE SAME
专利权人:
ONCOTHERAPY SCIENCE; INC.
发明人:
NAKAMURA, YUSUKE,TSUNODA, TAKUYA,OHSAWA, RYUJI,YOSHIMURA, SACHIKO,WATANABE, TOMOHISA
申请号:
SG2012039285
公开号:
SG181108A1
申请日:
2010.12.02
申请国别(地区):
SG
年份:
2012
代理人:
摘要:
Peptide vaccines against cancer are described herein. In particular, epitope peptides derived from the MYBL2 gene that bind to HLA antigen and have cytotoxic T lymphocyte (CTL) inducibility, more particularly peptides having the amino acid sequence of SEQ ID NO: 5 and fragments thereof, are provided. The present invention further extends to peptides that include one, two, or several amino acid insertions, substitutions or additions to the aforementioned peptides or fragments, provided they retain cytotoxic T cell inducibility. Also provided as nucleic acids encoding any of the aforementioned peptides, antigen-presenting cells and isolated CTLs that target such peptides, and pharmaceutical agents and compositions including any of the aforementioned peptides, nucleic acids, and APCs as active ingredients. The components of the present invention have particular utility in connection with the treatment and/or prophylaxis (i.e., prevention) of cancers (tumors), and/or the prevention of a postoperative recurrence thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充