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Agent for alleviating wrinkles
专利权人:
Makoto Tsunenaga;Chika Katagiri;Mikiko Kaminuma;Masaru Suetsugu
发明人:
Makoto Tsunenaga,Mikiko Kaminuma,Masaru Suetsugu,Chika Katagiri
申请号:
US12530841
公开号:
US08173705B2
申请日:
2008.03.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides an agent for preventing and alleviating wrinkles which has excellent effects of preventing and alleviating wrinkles formed by decreased barrier function of the skin owing to aging or photo aging, that is graphic wrinkles or linear wrinkles. The agent for preventing and alleviating wrinkles consisting of one or more compounds selected from the group consisting of gamma-aminobutyric acid derivatives represented by the following formula (1) or N,N,N-trimethyl gamma-aminobutyric acid represented by the following formula (3) and salts thereof:wherein R1 and R2 independently represent any of a hydrogen atom, an alkyl group having 1 to 3 carbon atoms, a benzyloxycarbonyl group, a cyclohexyl group, a cyclohexanemethyl group, a cyclohexanecarbonyl group, a guanidino group formed with nitrogen atom in the formula (1), an ureido group formed with nitrogen atom in the formula (1), and a group represented by following formula (2). Additionally, R1 and R2 may jointly form a piperidine ring, morpholine ring, or pyrrolidine ring. Both of R1 and R2 are not simultaneously a hydrogen atom.
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