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METHOD FOR TREATING HYPECORTISOLEMIA, HEADACHES, NEUROPATHIC PAIN AND RELATED DISORDERS
专利权人:
ИНДЭС БАЙОТЕК ПРАЙВЕТ ЛИМИТЕД (IN)
发明人:
БАСКАРАН Сунил (IN),ВИШВАРАМАН Мохан (IN)
申请号:
RU2013158302/15
公开号:
RU2013158302A
申请日:
2011.07.14
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A method of treating a disease condition selected from the group comprising hypercortisolemia, headache and neuropathic pain, or any combination of these conditions, which comprises administering a pharmaceutically effective amount of a composition comprising asiaticoside and madecassoside, optionally in combination with at least one excipient, in need of this subject. 2. The method according to claim 1, wherein the asiaticoside is in a concentration in the range of about 15% to 50%, and the madecassoside is in the concentration in the range of about 20% to 50%. The method of claim 1, wherein the composition is obtained from a Centella Asiatica plant. The method according to claim 1, wherein the state of hypercortisolemia is Cushing's syndrome. The method of claim 1, wherein the headache condition is selected from the group comprising migraine, tension headache and cluster headache, or any combination thereof. The method of claim 1, wherein the composition is administered at a dose in the range of about 1 mg / kg to about 100 mg / kg body weight per day. The method of claim 1, wherein the subject is an animal or human. The method according to claim 1, whereby the excipient is selected from the group consisting of granulating agents, binders, lubricants, disintegrants, sweeteners, glidants, release agents, antistatic agents, surfactants, antioxidants, gums, coating agents, coloring agents, flavoring agents, plasticizing agents, preservatives, suspending agents, emulsifiers, plant cellulosic material and means for spheronization or any combination thereof�1. Способ лечения болезненного состояния, выбранного из группы, включающей гиперкортизолемию, головную боль и нейропатическую боль или любую комбинацию этих состояний, который включает введение фармацевтически эффективного количества композиции, содержащей азиатикозид и мадекассозид, необязательно в сочетании, по меньшей мере, с одним эксципиентом, нуждающемуся в этом субъекту.2. Способ по п.1, согласно которому а
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