A kind of composition to treating cancer disclosed herein, it includes the novel combinations of triterpenoid. This novel triterpenoid combination include at least ganoderic acid S (ganoderic acid S,GAS), ganoderic acid T (ganoderic acid T,GAT), ganoderic acid Me (ganoderic acid Me,GAMe), ganoderic acid R (ganoderic acid R,GAR), red clever acid S (ganodermic acid S, GMAS). Disclosed composition can be used to treat or prevent the carcinoma of the rectum, liver cancer, breast cancer, lung cancer or leukemia.本文揭示一種用以治療癌症的組合物,其包含三萜化合物的新穎組合。此新穎的三萜化合物組合至少包含靈芝酸 S(ganoderic acid S, GAS)、靈芝酸 T(ganoderic acid T, GAT)、靈芝酸 Me(ganoderic acid Me, GAMe)、靈芝酸 R(ganoderic acid R, GAR)、赤靈酸 S(ganodermic acid S, GMAS)。所揭示組合物可用來治療或預防 直腸癌、肝癌、乳癌、肺癌或血癌。