Xin Chen,Maiko C. Hermsmeier,Diana Lac,Douglas W. Thomas,Noymi Yam,Akira Yamamoto
申请号：
US15910978
公开号：
US20180185394A1
申请日:
2018.03.02
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided herein is a topical composition and related methods for making and using the composition. In a first aspect, the topical composition comprises minocycline, a magnesium salt, and a sulfite compound in a non-aqueous solvent. In yet another aspect, the topical composition comprises a tetracycline-class drug, a source of magnesium, a monohydric aliphatic alcohol, and a polyol, wherein (i) the ratio between the monohydric aliphatic alcohol and the propylene glycol is in the range of 1:1 to 99:1 by weight and (ii) the tetracycline-class drug is dissolved in the topical composition.
