Humanized anti-HMGB1 antibody or antigen-binding fragment thereof

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专利权人:

National University Corporation Okayama University;Evec Inc.

发明人:

Takada, Kenzo,Torashima, Takashi,Nishibori, Masahiro

申请号：

AU2013375015

公开号：

AU2013375015A1

申请日:

2013.12.06

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

The present invention provides: a humanized anti-HMGB1 antibody that binds specifically to a sequence consisting of an eight-amino-acid residue (EEEDDDDE) at the C terminal of the HMGB1 protein, and that is effective in the treatment or prophylaxis of various inflammatory diseases related to said protein； an antigen-binding fragment of said antibody； and a pharmaceutical composition including said antibody or said antigen-binding fragment thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/