Steven A. Rosenberg,Richard A. Morgan,Timothy L. Frankel,Peter Peng
申请号：
US13146531
公开号：
US20120015888A1
申请日:
2010.01.25
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention provides T cell receptors (TCRs) having antigenic specificity for a cancer antigen, e.g., tyrosinase. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, and pharmaceutical compositions. The invention further provides a method of detecting the presence of cancer in a host and a method of treating or preventing cancer in a host using the inventive TCRs or related materials.
