An analog front-end system and method for Electromyography (EMG) signal acquisition in wearable applications. The system includes filters for restricting the bandwidth of captured EMG signals, a multiplexer, an amplifier, and a microcontroller unit having an analog-to-digital converter for converting the analog EMG signals into digital signals. In the system and method, the bandwidth of the EMG signals is filtered before the EMG signals are multiplexed by the multiplexer, and the EMG signals are multiplexed by the multiplexer so that one amplifier is used for amplifying the EMG signals before they reach the analog-to-digital converter. The EMG signals are acquired by multilayered sensors applied to wearable apparel, and a connector transfers the body signals from the multilayered sensors to a central device having the analog front-end system for computing, monitoring, and sending the body signals to a display.