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OCTAPOD IRON OXIDE NANOPARTICLES AS HIGH PERFORMANCE T2 CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING
专利权人:
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV;XIAMEN UNIVERSITY
发明人:
Jinhao Gao,Xiaoyuan Chen,Zenghuan Zhao
申请号:
US14895745
公开号:
US20160129138A1
申请日:
2013.06.03
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Disclosed are nanoparticles comprising octapod iron oxide having eight trigonal bipyramidal arms and a method of preparing the same. The nanoparticles are prepared by heating a mixture of a ferric carboxylate, a carboxylic acid, a chloride salt, water, and a non-polar solvent, to a temperature above about 300° C. Also disclosed is a method of magnetic resonance imaging a tissue in a mammal, comprising use of the aforesaid nanoparticles.
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