MicroRNA compounds and methods for modulating miR-21 activity

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专利权人:

Regulus Therapeutics Inc.

发明人:

BHAT, Balkrishen

申请号：

AU2017219156

公开号：

AU2017219156A1

申请日:

2017.08.29

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

#$%^&*AU2017219156A120170921.pdf#####MICRORNA COMPOUNDS AND METHODS FOR MODULATING MIR-21 ACTIVITY ABSTRACT Described herein are compositions and methods for the inhibition of miR-21 activity. The compositions have certain nucleoside modification patterns that yield potent inhibitors of miR-21 activity. The compositions may be used to inhibit miR-2 1, and also to treat diseases associated with abnormal expression of miR-2 1, such as fibrosis and cancer. H1'1 T7AA

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