The invention provides substituted cyclohexyl-1,4-diamine derivatives offormula I:(see formula I)The derivatives may be used to produce pharmaceutical compositions,and these compositions may be used to treat pain, anxiety, stress, a stress-relatedsyndrome, depression, epilepsy, Alzheimer's disease, senile dementia,catalepsy,general cognitive dysfunction, learning difficulties as a nootropic, memorydifficultiesas a nootropic, withdrawal symptoms, alcohol-abuse, drug-abuse, medicine-abuse,alcohol-dependency, drug-dependency, medicine-dependency, sexual dysfunction,acardiovascular disease, hypotension, hypertension, tinnitus, pruritus,migraine,hearing difficulties, deficient intestinal motility, impaired absorption ofnutrients,anorexia, obesity, a locomotive disorder, diarrhoea, cachexia, or urinaryincontinence.
