Macdonald, Lynn,Murphy, Andrew J.,McWhirter, John,Tu, Naxin,Voronina, Vera,Gurer, Cagan,Meagher, Karolina A.,Stevens, Sean
申请号:
AU20160202512
公开号:
AU2016202512(C1)
申请日:
2016.04.20
申请国别(地区):
澳大利亚
年份:
2018
代理人:
摘要:
The invention provides a genetically modified non-human animal that comprises in its genome unrearranged T cell receptor variable gene loci, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified non-human animal and methods of making the same. Various methods of using the genetically modified non-human animal are also provided.