NOVEL CURCUMIN DERIVATIVES AS DRUG CANDIDATES TO INHIBIT THE ACTIVATOR PROTEIN-1 (AP1): TO AID TREATMENT OF CANCER

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专利权人:

发明人:

K SANTOSH KUMAR

申请号：

IN201741001911

公开号：

IN201741001911A

申请日:

2017.01.18

申请国别(地区):

IN

年份:

2018

代理人:

摘要：

The invention relates to two novel compounds derived from Curcumin a curcuminoid of turmeric as drug candidates for cancer treatment. Cancers share some common pathogenic mechanism at the level of cell signaling and transcription. Hence, a drug which can act at this level can be used to treat cancer. The activator protein - 1 (AP1) is a transcription factor and consists of either homodimers or heterodimers of the Jun and Fos family proteins. The two novel derivatives of Curcumin can be effective drug candidates for inhibition of AP1 and can provide a promising solutionto treat cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/