PROTUTIJELA KOJA NEUTRALIZIRAJU GP120 I NJIHOVA UPOTREBA

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专利权人:

The United States of America; as represented by the Secretary; Department of Health and Human Services

发明人:

Connors, Mark,Huang, Jinghe,KANG, Byong Ha,Mascola, John,Ishida, Elise,Zhou, Tongqing,Kwong, Peter,Zheng, Anqi

申请号：

HRP20200583

公开号：

HRP20200583T1

申请日:

2020.04.10

申请国别(地区):

HR

年份:

2020

代理人:

摘要：

Antibodies and antigen binding fragments that specifically bind to gp120 and neutralize HIV-1 are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed.

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