A wound treatment system includes a sponge including a first surface adapted to confront a wound bed of a patient, a drape in contact with a second surface of the sponge, and a vacuum source for distributing a vacuum force through the sponge. The system also includes a wound separator having a sidewall defining an interior chamber, wherein at least a portion of an exterior of the sidewall confronts at least an interior portion of the sponge. An ostomy appliance is operatively connected to the wound separator to receive substances passing out of the wound separator.