Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.;Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Universitätsmedizin
发明人:
Ernst Bamberg,Phil Wood,Thomas Mager,Tobias Moser,David Lopez de la Morena
申请号:
US16306652
公开号:
US20190218271A1
申请日:
2017.06.02
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention relates to mutant light-inducible ion channels having improved properties as compared to the parent channel, nucleic acid constructs encoding same, expression vectors carrying the nucleic acid construct, cells comprising said nucleic acid construct or expression vector, and their respective uses, as well as non-human animals comprising the mutant light-inducible ion channel, the nucleic acid construct or the expression vector as disclosed herein.