The present invention is a stable preparation of an antibody against a T cell immunoreceptor having an Ig and ITIM domain (TIGIT), which further comprises an anti-human programmed death receptor 1 (PD-1) antibody or an antigen-binding fragment thereof. It may also relate to said formulation. Also provided are methods of treating various cancers and chronic infections with the formulations of the present invention. [Selection diagram] Figure 1本発明は、ＩｇおよびＩＴＩＭドメインを有するＴ細胞免疫受容体（ＴＩＧＩＴ）に対する抗体の安定な製剤であって、抗ヒトプログラム死受容体１（ＰＤ－１）抗体またはその抗原結合性断片をさらに含有してもよい前記製剤に関する。また、様々ながんおよび慢性感染症を本発明の製剤で処置する方法も提供される。【選択図】図１
