Disclosed herein are pharmaceutical compositions comprising a. (+)-2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-4-acetylaminoisoindoline-1,3-dione, or a pharmaceutically acceptable salt thereof, a filler, a disintegrant and a lubricant and b. a coating formulation comprising polyvinyl alcohol. Also disclosed is the use of the compositions in treatment of conditions such as psoriasis, dermatitis and arthritis.