Piet Herdewijn;Thierry Andre Michel Louat;Mi-Yeon Jang;Steven De Jonghe;Yuan Lin;Ling-Jie Gao;Bart Vanderhoydonck;Mark Jozef Albert Waer;Jean Ferdinand Herman
发明人:
Piet Herdewijn,Steven De Jonghe,Ling-Jie Gao,Mi-Yeon Jang,Bart Vanderhoydonck,Mark Jozef Albert Waer,Yuan Lin,Jean Ferdinand Herman,Thierry Andre Michel Louat
申请号：
US13255429
公开号：
US20120046278A1
申请日:
2010.03.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to compound of formula I, II, III, or IV, and/or a pharmaceutical acceptable addition salt thereof and/or a stereoisomer thereof and/or a solvate thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R11, and R12 are as defined in the claim 1. The present invention also relates to a method for their preparation, as well as to pharmaceutical compositions thereof. The present invention further relates to the use of said compounds as biologically active ingredients, more specifically as medicaments for the treatment of disorders and pathologic conditions such as, but not limited to, immune and auto-immune disorders, organ and cells transplant rejections.
