Pancreatic islets of transgenic LEA29Y animals for treating diabetes

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专利权人:

发明人:

Eckhard Wolf,Nikolai Klymiuk,Lelia Wolf-van Buerck,Jochen Seissler

申请号：

US13659523

公开号：

US20140112958A1

申请日:

2012.10.24

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention relates to methods of treating diabetes in a human subject comprising the use of pancreatic islets or of embryonic pancreatic tissue of a transgenic animal, wherein said transgenic animal contains a polynucleotide sequence encoding a CTLA4 peptide-immunoglobulin fusion, preferably LEA29Y, and expresses said CTLA4 peptide-immunoglobulin fusion in a tissue-specific manner in pancreatic islets.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/