NISSAN CHEMICAL INDUSTRIES, LTD.;REPROCELL INCORPORATED
发明人:
申请号：
EP11845184.8
公开号：
EP2647697B1
申请日:
2011.12.01
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
An expanding agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful as a therapy for various hematopoietic diseases and useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy is provided. A method of producing hematopoietic stem cells and/or hematopoietic progenitor cells, which comprises expanding hematopoietic stem cells by culturing hematopoietic stem cells ex vivo in the presence of a compound represented by the formula following (I), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof (wherein R 1 to R 8 are as defined in the description).
