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Compositions and methods for treating neuropsychiatric disorders using an endothelin-B receptor agonist
专利权人:
MIDWESTERN UNIVERSITY
发明人:
Gulati, Anil
申请号:
AU2014287427
公开号:
AU2014287427B2
申请日:
2014.07.08
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The present invention relates to compositions and methods for treating neuropsychiatric disorders in vertebrates and humans. More specifically, the present invention provides for use of IRL-1620, an endothelin-B receptor agonist, in appropriate doses to be a neuroprotective and a neuroregenerative agent. Accordingly, in one aspect the disclosure provides a method of treating a neuropsychiatric disorder comprising administering to a patient in need thereof a therapeutically effective amount of an endothelin-B receptor agonist to treat the neuropsychiatric disorder. In some embodiments, the endothelin-B receptor agonist is co-administered with an additional agent to treat the neuropsychiatric disorder. In some embodiments, the additional agent is selected from the group consisting of an antidepressant, an anti-inflammatory agent, a CNS stimulant, a neuroleptic, and an anti-proliferative agent.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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