SANTEN PHARMACEUTICAL CO., LTD.;ASAHI GLASS CO LTD
发明人:
ROPO, AULI
申请号:
CA2735825
公开号:
CA2735825C
申请日:
2009.09.04
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention provides a new pharmaceuticalapplication of a 15,15-difluoroprostaglandin F2.alpha. derivative.As a result of intensive studies in order to find a newpharmaceutical application of a 15,15-difluoroprostaglandinF2.alpha. derivative, it was found that, in a European Phase IIIclinical trial for tafluprost, one of the15,15-difluoroprostaglandin F2.alpha., derivatives, with patientswith open-angle glaucoma or ocular hypertension, tafluprosthas actions of growing eyelashes, making eyelashes thicker,and changing the color thereof, that is, has an effect ofpromoting the growth of hair (eyelashes). Therefore, a15, 15-difluoroprostaglandin F2.alpha., derivative is useful as a hairgrowth promoting agent, and is expected to be useful as anactive ingredient of a preventive or therapeutic agent for adisease associated with hair such as alopecia and a hair careproduct or a hair cosmetic product for regrowing hair, growinghair, increasing hair density, nourishing hair, or the like.