Frank Ebetino,Robert Boeckman,Lianping Xing,Lifeng Xiao,Brendan Boyce
申请号：
US15772910
公开号：
US20180318425A1
申请日:
2016.11.02
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides compositions and methods for providing controllable local delivery of a conjugate of bortezomib (Btz) and a bisphosphonate to promote bone formation. In certain embodiments, the invention is used as a treatment for a subject with diseases and disorders characterized by bone loss.
