Nucleic acids encoding vitamin K expoxide reductase subunit 1 and vitamin K dependent protein expression and methods of using same

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专利权人:

Ernst Boehm;Friedrich Scheiflinger

发明人:

Friedrich Scheiflinger,Ernst Boehm

申请号：

US11342299

公开号：

US09617523B2

申请日:

2006.01.27

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The present invention relates to a host organism containing recombinant nucleic acids coding for the vitamin K reductase complex subunit 1 (VKORC1) and recombinant nucleic acids coding for a vitamin K dependent (VKD) protein, wherein both the recombinant VKORC1 and the recombinant VKD protein are expressed in said host organism. Further, the present invention relates to a cell culture system comprising cells which contain said recombinant nucleic acids and to methods for improving the productivity of recombinant VKD protein expression in a host organism being cultured in suitable systems.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/