University of Maryland, Baltimore;The United States Government as represented by the Department of Veterans Affairs
发明人:
Kamal D. Moudgil,Rakeshchandra R. Meka
申请号：
US16825371
公开号：
US20200297633A1
申请日:
2020.03.20
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates in part to compositions for targeted delivery of an agent and agent delivery systems comprising a novel tissue-targeting peptide ligand (CKPFDRALC) named ART-2. In certain aspects, the ART-2-coated liposomes encapsulating an agent, such as a therapeutic agent, diagnostic agent, imaging agent, or any combination thereof, were more effective in inhibiting, diagnosing, or imaging a disease or disorder, such as an arthritis progression, than control, despite a comparable safety profile.
