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PHARMACEUTICAL COMPOSITIONS CONTAINING BRADYKININ ANTAGONISTS AND HYALURONIC ACID, AND USAGE THEREOF
专利权人:
INSTITUTO LUSO FARMACO D’ITALIA S.P.A.
发明人:
MAGGI, CARLO ALBERTO,GIULIANI, SANDRO,QUARTARA, LAURA
申请号:
GEAP2008011807
公开号:
GEP20125602B
申请日:
2008.11.10
申请国别(地区):
GE
年份:
2012
代理人:
摘要:
There are represented pharmaceutical compositions as active ingredients containing mixture of: a) hyaluronic acid or salts thereof chosen from sodium or potassium salts; and b) bradykinin B2 receptor antagonist of formula (I), with pharmaceutically acceptable carrier or excipient wherein hyaluronic acid as polymer is available within MW 0.5-10 million dalton, and bradykinin antagonist values are chosen from values defined in the claims (see the claims), pharmaceutically acceptable salts thereof, enantiomers, enantiomer mixtures thereof, and their usage at the treatment of osteoarthritis and posttraumatic osteoarthritis.
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