The Prince Of Songkla University;Thailand Center of Excellence for Life Sciences
发明人:
申请号:
EP16915342.6
公开号:
EP3510052A4
申请日:
2016.09.02
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present disclosure provides for the method of preparing, from serum of calendered acidified Hevea latex, an extract that is rich in low-molecular weight carbohydrates and having anti-cancer activity. The method comprises the steps of: obtaining the serum released when acidified Hevea latex is calendered; optionally removing debris and micro-organisms from the serum; removing proteins; removing quebrachitol and small polar molecules; optionally dissolving the remaining solid powder in water; further removing proteins by treatment with acid; optionally neutralizing the excess acid; precipitating with solvent; collecting the precipitate; and optionally freeze drying the precipitate. The disclosure also provides for the method of treating cancer growth and/or metastasis and the method of inhibiting tumor cell proliferation in a patient. Furthermore, there are provided a pharmaceutical composition and a functional food composition comprising the disclosed extract of Hevea latex.