Banci, Lucia,Cantini, Francesca,Dragonetti, Sara,Gentile, Maria Antonietta,Veggi, Daniele,Scarselli, Maria,Pizza, Mariagrazia
申请号:
AU2015200160
公开号:
AU2015200160A1
申请日:
2015.01.14
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
#$%^&*AU2015200160A120150305.pdf#####ABSTRACT The invention is in the field of immunisation and, in particular, immunisation against diseases caused by pathogenic bacteria in the genus Neisseria, such as N. meningitides (meningococcus). It is an object of the invention to provide modified fHBPs which, compared to wild-type fHBPs, show reduced binding to fH while maintaining the ability to elicit bactericidal anti-fHBP antibodies.