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Rusztowanie kostne na bazie ß-1,3-glukanu (kurdlanu) i bioceramiki oraz sposób jego wytwarzania
专利权人:
UNIWERSYTET MEDYCZNY W LUBLINIE
发明人:
KATARZYNA KLIMEK,AGATA PRZEKORA,GRAŻYNA GINALSKA
申请号:
PL415936
公开号:
PL415936A1
申请日:
2016.01.27
申请国别(地区):
PL
年份:
2017
代理人:
摘要:
bone scaffold based on bioceramiki fosforanowo - calcium and kurdlanu, characterised by the fact that contains 6 - 20% (w \/ v) solution of beta - 1,3 - glucan hereinafter kurdlanem, prepared in 0.1 - 0.5 m sodium (naoh) solution for good 0.3 m (x component) and 2 - 90% (in \/ (v) bioceramiki fos foranowo - calcium rozprowadzonej in kurdlanu prepared solution, in the form of nanoproszku,powder or granules, the size of 0.1 - 1.0 mm fired at temperatures 500\u00b0c - 1300\u00b0c, favourably 1100 - 1200\u00b0c (component s), with the balance weight when the fixed components are respectively 7 - 10% kurdlanu and 60 - 80% bioceramiki and maximum component y (g the kurdlanu per 100 ml of solution in naoh), depending on the component x (in grams per 100 ml of naoh),results from the formula: ymax (x) = 0079x2 - 61557x + 123,57. the subject application is also a way of manufacturing scaffolding marrow based on bioceramiki fosforanowo - calcium and kurdlanu.the prepared material due to its biological properties, suitable for use both in vitro tissue engineering bone as scaffold, pre zasiedlane cells osteoprogeniterowymi, derived from your body in order to generate the so-called.be alive, and in vitro in regenerative medicine, as material catalyst regeneration processes at the site of implantation. furthermore, the prepared material is suitable for use as a base for chemical restraint bio active substances, also termowra\u017cliwych (e.g.adhesive proteins, growth factors, antibiotics peptide), method pu\u0142apkowania inside structure polymer gel kurdlanowego (at the manufacturing stage scaffolding marrow), which will improve its biological properties and protect against post - operational infek the.Rusztowanie kostne na bazie bioceramiki fosforanowo - wapniowej i kurdlanu, charakteryzuje się tym, że zawiera 6 - 20% (w/v) roztwór ß-1,3-glukanu zwany dalej kurdlanem, przygotowany w 0,1 - 0,5 M roztworze zasady sodowej (NaOH), korzystnie 0,3 M (komponent x) oraz 2 - 90% (w/v) bi
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