The invention relates to antibacterial compounds formula I wherein R1 is the group M, whereby M is one of the groups MA and MB represented below wherein A is a bond or C≡C； R1A is H or halogen； R2A is H or halogen； R3A is H, alkoxy, hydroxyalkoxy, hydroxyalkyl, dihydroxyalkyl, 2-hydroxyacetamido, substituted cycloprop-1-yl or substituted oxetan-3-yl； and R1B is hydroxyalkyl, dihydroxyalkyl, aminoalkyl, dialkylaminoalkyl, substituted cycloprop-1-yl, substituted cyclobutan-1-yl, substituted oxetan-3-yl, 3-hydroxythietan-3-yl, substituted azetidin-3-yl, trans-(cis-3,4-dihydroxy)-cyclopent-1-yl, 3-hydroxymethylbicyclo[1,1,1]pentan-1-yl, 4-hydroxytetrahydro-2H-pyran-4-yl,(3R,6S)-3-aminotetrahydro-2H-pyran-6-yl, piperidin-4-yl or 1-(2-hydroxyacetyl)piperidin-4-yl； and salts thereof.本發明係關於式I之抗菌性化合物其中R1係基團M，其中M係下文代表之基團MA及MB中之一者：其中A係鍵或C≡C；R1A係H或鹵素；R2A係H或鹵素；R3A係H、烷氧基、羥基烷氧基、羥基烷基、二羥基烷基、2-羥基乙醯胺基、經取代環丙-1-基或經取代氧雜環丁-3-基；且R1B係羥基烷基、二羥基烷基、胺基烷基、二烷基胺基烷基、經取代環丙-1-基、經取代環丁-1-基、經取代氧雜環丁-3-基、3-羥基硫雜環丁-3-基、經取代氮雜環丁-3-基、反式-(順式-3,4-二羥基)-環戊-1-基、3-羥甲基二環[1,1,1]戊-1-基、4-羥基四氫-2H-吡喃-4-基、(3R,6S)-3-胺基四氫-2H-吡喃-6-基、六氫吡啶-4-基或1-(2-羥基乙醯基)六氫吡啶-4-基；及其鹽。
