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METHOD FOR PREPARING HYALURONIC ACID DERMAL FILLERS, DERMAL FILLERS OBTAINED THEREBY AND THEIR USE
专利权人:
Merz Pharma GmbH &; Co. KGaA
发明人:
Nadine HAGEDORN,Roland STRAGIES,Lubin BELKOVI,Radia EL-BANNA
申请号:
US16344941
公开号:
US20190269582A1
申请日:
2017.11.02
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention generally relates to the field of hyaluronic acid (HA) dermal fillers, and more specifically to methods for preparing crosslinked HA-based compositions in the form of a gel comprising high-temperature dialysis and/or crosslinking in the presence of phosphate and an alkaline metal halide salt. The present invention further relates to crosslinked HA-based gel compositions prepared by said methods and their use as dermal fillers in aesthetic applications such as wrinkle treatments.
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