Mitchell, Helen,Fraley, Mark E.,Cooke, Andrew J.,Chen, Yi-Heng,Stump, Craig A.,Zhang, Xu-Fang,McComas, Casey C.,Schirripa, Kathy,McWherter, Melody,Mercer, Swati P.,Babaoglu, Kerim,Meng, Dongfang,Wu, J
申请号:
AU2015236428
公开号:
AU2015236428A1
申请日:
2015.03.23
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The present invention is directed to six membered heteroaryl benzamide compounds of formula (I), which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.