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Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors
专利权人:
Malcolm Clive Carter;George Stuart Cockerill;Karen Elizabeth Lackey
发明人:
Malcolm Clive Carter,George Stuart Cockerill,Karen Elizabeth Lackey
申请号:
US12691784
公开号:
US08513262B2
申请日:
2010.01.22
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A process for the preparation of a compound of formula (I)comprising the steps:(a) reacting a compound of formula (II)wherein L and L′ are suitable leaving groups,with a compound of formula (III)UNH2  (III)to prepare a compound of formula (IV)and subsequently (b) substituting the group R1 by replacement of the leaving group L′.
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