The General Hospital Corporation d/b/a Massachusetts General Hospital;RaNA Therapeutics; Inc.;RaNA Therapeutics, Inc.
发明人:
Krieg, Arthur M.,Subramanian, Romesh,McSwiggen, James,Lee, Jeannie T.
申请号：
AU2013262706
公开号：
AU2013262706A1
申请日:
2013.05.16
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
Aspects of the invention provide single stranded oligonucleotides for activating or enhancing expression of PTEN. Further aspects provide compositions and kits comprising single stranded oligonucleotides for activating or enhancing expression of PTEN. Methods for modulating expression of PTEN using the single stranded oligonucleotides are also provided. Further aspects of the invention provide methods for selecting a candidate oligonucleotide for activating or enhancing expression of PTEN.
