Memorial Sloan Kettering Cancer Center;Massachusetts Institute of Technology
发明人:
Sarah CHEAL,Hong XU,Steven LARSON,Nai-Kong CHEUNG,Karl Dane WITTRUP,Alice TZENG
申请号：
US15549638
公开号：
US20200140543A1
申请日:
2016.02.09
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Described herein are multi-specific binding agents that bind A33 and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. Also provided herein are methods of using multi-specific binding agents or compositions thereof for the detection, prevention, and/or therapeutic treatment of diseases characterized by expression of the A33 glycoprotein antigen, in particular, colorectal cancer.
