A device for testing for the presence of neuropathy by applying a thermal stimulus to a test area of skin includes a temperature sensing arrangement for determining a reference temperature being a reference skin temperature or room temperature, a thermal stimulus application arrangement and a temperature controlling arrangement for controlling temperature of the thermal stimulus. The reference temperature is used in controlling the temperature of the applied thermal stimulus. The device may include a blood flow sensing arrangement which provides a measurement of blood flow in an area of the skin which may be considered to be indicative of a blood flow in response to an applied stimulus.