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液体経口製剤
专利权人:
ライオン株式会社
发明人:
吉田 雅貴,木津 典生
申请号:
JP2014140373
公开号:
JP6335692B2
申请日:
2014.07.08
申请国别(地区):
JP
年份:
2018
代理人:
摘要:
PROBLEM TO BE SOLVED: To provide a liquid oral formulation in which the elution of a water-soluble active ingredient of a drug (&alpha) included in a microcapsule (A) can be inhibited, and the adhesion of the ingredient (A) to a container can be inhibited.SOLUTION: The invention relates to a liquid oral formulation in which a microcapsule (A) and xanthan gum (B) are dispersed in an aqueous medium. The microcapsule (A) has a water-soluble active ingredient of a drug (&alpha) included in a coating ingredient (&bgr), and has a volume median diameter of 150-1000 &mum. The coating ingredient (&bgr) has a melting point of 50°C or more, and is at least one kind selected from the group consisting of ester of a higher fatty acid and a higher alcohol, vegetable oil and hydrogenated oil thereof, animal oil and hydrogenated oil thereof, a higher fatty acid and a higher alcohol. Preferably, the liquid oral formulation has a viscosity at 25°C is 10-1000 mPa s. Preferably, the liquid oral formulation is stored in a glass container.SELECTED DRAWING: None
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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