KELLER, Gordon,NOSTRO, Maria Cristina,HOLTZINGER, Audrey,SARANGI, Farida
申请号：
LT13784648
公开号：
LT2844739T
申请日:
2013.04.30
申请国别(地区):
LT
年份:
2019
代理人:
摘要：
Methods and compositions for producing NKX6-1+ pancreatic progenitor cells and/or insulin producing cells from an endodermal cell population, the method comprising contacting the endodermal cell population with an EGF component, a Nicotinamide component and/or a Noggin component, optionally a combination of at least one EGF component and at least one nicotinamide component to induce the differentiation of at least one endodermal cell into a NKX6-1+ pancreatic progenitor cell, the combination optionally further comprising at least one Noggin component.
