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PAMAM, SPACER MOLECULE AND CAFESTOL POLYMERS
专利权人:
发明人:
Leonardo S. SANTOS,John AMALRAJ,Esteban F. DURAN LARA,Fabiane M. NACHTIGALL
申请号:
US13919403
公开号:
US20140371401A1
申请日:
2013.06.17
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention is directed to a polymeric compound with a size in a nanometric scale, useful as a biocompatible carrier for the transport and delivery of active agents into a fish, insect, animal, reptile, bird, human, or plant, wherein said polymeric compound comprises PAMAM (polyamidoamine) dendrimers, a spacer molecule, and cafestol, wherein the polymeric compound of the invention comprises a structure of the kind (cafestol-PAMAM derivative)2-spacer molecule. Use of the compound as a biocompatible carrier for transport and delivery of antithrombotic active agents is disclosed. Procedures for obtaining a polymeric compound comprising the activation of cafestol, activation of polyethylene glycol, and formation of cafestol-PAMAM-PEG-PAMAM-cafestol are also disclosed.
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中国工程科技知识中心
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