KNUST, HENNER,NETTEKOVEN, MATTHIAS,PINARD, EMMANUEL,ROCHE, OLIVIER,ROGERS-EVANS, MARK
申请号:
CA2713713
公开号:
CA2713713C
申请日:
2009.02.02
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to piperidine sulphonamide derivatives offormula (I) wherein Ar1, Ar2, R1, R2, m andn are as defined in the description and claims, or pharmaceutically suitableacid addition salts thereof. The compounds of formulaI are orexin receptor antagonists and the related compounds may be useful inthe treatment of sleep apnea, narcolepsy, insomnia,parasomnia, jet lag syndrome, circadian rhythms disorder or sleep disordersassociated with neurological diseases.