The system and method that is used for nasal irrigation is provided, and wherein the nasal irrigation device comprises that source of saline solution, effluent accepter, nasal interface, vacuum source, the nasal cavity by nasal interface and user make the fluid passage that source of saline solution communicates with the effluent accepter and be used for optionally controlling vacuum source and the switch and the valve module of the saline solution stream by fluid passage.The source of saline solution bottle is placed with respect to device, makes saline solution enter the nasal interface that engages with the nostril of installing user to provide gravity to induce.Gravity is induced and from the combination results fluid stream of the relative vacuum of effluent accepter, with flushing, clean and the nasal cavity and the aperture of massage user.