Pim kinase inhibitors and methods of their use

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专利权人:

Novartis AG

发明人:

Lan, Jiong,Lindvall, Mika,Tetalman, Michelle,Burger, Matthew,Nishiguchi, Gisele

申请号：

AU2009221134

公开号：

AU2009221134B2

申请日:

2009.03.03

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

The present invention relates to new compounds of Formulas (I) and (II), their tautomers, stereoisomers and polymorphs, and pharmaceutically acceptable salts, esters, metabolites or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the inhibition of Pirn kinase activity and/or the prophylaxis or treatment of cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/