PROBLEM TO BE SOLVED: To develop and provide a novel and useful ABCA12 gene expression enhancing agent which carries out an important role in maintaining lipid homeostasis, which has high usability and can be used in a wide range of industrial applications such as, not only pharmaceutical and food products (including food and drinks for beauty and health conscious), but also beverages, and external preparations such as cosmetics.SOLUTION: An ABCA12 gene expression enhancing agent comprises an extract from grape fruit, in particular Chardonnay or Niagara fruit pressed residue as an active ingredient.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】本発明は、新規かつ有用であり、脂質恒常性維持に重要な役割を果たすＡＢＣＡ１２遺伝子発現促進剤の開発と、それらの提供を目的とする。利用性が高く、医薬品、食品（美容や健康志向の飲食品を含む）のみならず、飲料、化粧料等外用剤といった産業上における広い範囲での応用が可能である。【解決手段】ブドウ果実、特にシャルドネまたはナイアガラ果実圧搾残渣からの抽出物を有効成分とするＡＢＣＡ１２遺伝子発現促進剤。【選択図】なし
