BROWN, Bob, D.,DUDEK, Henryk, T.,LAI, Cheng,H T 杜德克,LAI, Cheng,賴程
申请号:
HK18103821.9
公开号:
HK1244300A
申请日:
2018.03.19
申请国别(地区):
HK
年份:
2018
代理人:
摘要:
This invention relates to double-stranded nucleic acids that reduce expression of theLDHAgene by targeting lactate dehydrogenase mRNA for use in the treatment of PHI, PH2, PH3 (primary hyperoxaluria Type 1, Type 2 or Type 3) or idiopathic hyperoxaluria, e.g., Dicer substrate siRNA (DsiRNA) agents.